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Anti-MCPIP1 Polyclonal Antibody
產(chǎn)品簡介：

Anti-MCPIP1 Polyclonal Antibody
應用 WB IHC
稀釋比例WB 1:500-2000. IHC 1:20-50.
交叉反應Human

產(chǎn)品型號：K106615P

更新時間：2022-08-15

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產(chǎn)品介紹

Anti-MCPIP1 Polyclonal Antibody

英文名稱Anti-MCPIP1 Polyclonal Antibody
宿主Rabbit
別名dJ423B22.1;MCPIP;MCPIP1;dJ423B22.1;MCPIP;MCPIP-1;MCPIP1;Reg1
應用WB IHC
稀釋比例WB 1:500-2000. IHC 1:20-50.
交叉反應Human
蛋白分子量67kDa
Gene ID80149
保存Store at -20°C. Avoid freeze / thaw cycles.
儲存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原A synthetic peptide of human MCPIP1
性狀液體
Public Immunogen RangeA synthetic peptide of human MCPIP1
Subcellular LocationsCytoplasm Nucleus
Swiss ProtQ5D1E8
克隆類型Polyclonal Antibody
背景資料Endoribonuclease involved in various biological functions such as cellular inflammatory response and immune homeostasis, glial differentiation of neuroprogenitor cells, cell death of cardiomyocytes, adipogenesis and angiogenesis. Functions as an endoribonuclease involved in mRNA decay. Modulates the inflammatory response by promoting the degradation of a set of translationally active cytokine-induced inflammation-related mRNAs, such as IL6 and IL12B, during the early phase of inflammation. Prevents aberrant T-cell-mediated immune reaction by degradation of multiple mRNAs controlling T-cell activation, such as those encoding cytokines (IL6 and IL2), cell surface receptors (ICOS, TNFRSF4 and TNFR2) and transcription factor (REL) (By similarity).

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